Page 85 - Athletic Health Handbook
P. 85
MEDICAL CONDITIONS

BASIC SCIENCE AND
CLINICAL APPLICATIONS
OF PLATELET-RICH PLASMA

GRANT L. JONES, MD PLATELET-RICH PLASMA (PRP) is defined as a sample of
The Ohio State University
blood that has a platelet concentration above baseline levels. Platelet-rich
plasma, with a platelet concentration of at least 1,000,000 platelets/microL
in 5 ml of plasma has been shown to enhance healing of musculoskeletal
tissue due to its 3- to 5-fold increase in growth factor concentration.1,2

Platelet-rich plasma has been used in the fields of maxillofacial and
general surgery as well as orthopaedic surgery to aid in hemostasis,
wound healing, bone healing, and tendon healing. The use of PRP in
sports medicine has been recently popularized by its use in a Pittsburgh
Steelers’ football player prior to the 2009 Super Bowl to expedite the
healing of acute medial collateral ligament (MCL) injury. This article
reviews the basic science and clinical applications of PRP.

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