Page 89 - Athletic Health Handbook
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the list of banned substances for the these clinical studies are case series
various professional leagues.3 So far, with small sample sizes and no control
in the current literature, there is no groups. More Level I randomized,
evidence that there is any systemic or controlled clinical studies are needed
performance-enhancing effect to PRP. with sufficient sample sizes to more
But, the ethics of its use needs to be clearly determine the effectiveness
more clearly defined in the future. of PRP. Presently, the author of this
article is involved in a multi-center
Conclusions double-blinded, randomized,
controlled study on the use of PRP
Overall, based on in vitro and in vivo for the treatment of patients with
animal studies, PRP shows promise chronic lateral epicondylitis who
in treating chronic tendinopathy, have failed traditional treatment
acute ligament, and acute muscle measures. We are still enrolling
disorders and enhancing the healing patients to obtain a statistically
of surgical repairs and reconstructions. adequate sample size, but hopefully
Also, there is some clinical evidence our study will help answer some
to suggest that its use may be of of these questions once we obtain
benefit when treating the above our complete cohort of patients.
disorders. However, a majority of

BASIC SCIENCE AND CLINICAL APPLICATIONS OF PLATELET-RICH PLASMA 89
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